Skin prick tests and radioallergosorbent tests (RAST) or CAP fluoroimmunoassay may be requested if a drug, latex, or food allergy is suspected in acute urticaria. There are no routine diagnostic tests in chronic spontaneous urticaria apart from blood count and C-reactive protein (CBC, CRP ), but investigations may be undertaken if an underlying disorder is suspected.
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A radioallergosorbent test (RAST) is an assay used to detect the allergen specific IgE antibodies in the bloodstream. This is the most common diagnostic method performed for evaluation of allergies. RAST aids in differential diagnosis of allergies (especially food allergies), atopic asthma, natural rubber latex allergies, and psoriasis.
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